✦ Interactive Calculator

GLP-1 Half-Life
Calculator

Enter your last injection date and see exactly how much medication remains in your system — and when it will be fully cleared.

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Half-Life Calculator

How Much Is Still in My System?

Based on published pharmacokinetic data. Results are estimates — individual metabolism varies.

The most recent dose you took
Still in System
Days Since Last Dose
Fully Cleared By
Days Until Cleared
Clearance Timeline (5 Half-Lives)
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Reference

Half-Life Data by Medication

Based on FDA prescribing information and published pharmacokinetic studies.

MedicationHalf-LifeTime to Steady StateTime to Full Clearance
Semaglutide (all forms)~7 days4–5 weeks~5 weeks after stopping
Tirzepatide (all forms)~5 days4 weeks~4 weeks after stopping
Ozempic® / Wegovy®~7 days4–5 weeks~5 weeks after stopping
Mounjaro® / Zepbound®~5 days4 weeks~4 weeks after stopping
⚠️ Half-life estimates are population averages. Individual clearance depends on kidney function, body weight, and metabolism. Always consult your provider before stopping or switching medications.
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Medical Disclaimer This calculator provides estimates based on published pharmacokinetic data and is for educational purposes only. It does not constitute medical advice. Individual drug metabolism varies significantly. Always consult your prescribing provider before making any changes to your medication.